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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Normal Saline vs Lactated Ringers - #PHARMFAX
There has been a change of preference of fluids from normal saline to lactated ringers. There has been a change of preference of...
Jul 25, 20231 min read


Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...
Jul 24, 20231 min read


High-Dose Insulin for Overdoses - #PHARMFAX
BB and CCB overdoses progress into cardiogenic shock. BB inhibit catecholamines from binding to beta receptors, while CCB block SA and...
Jul 24, 20232 min read


Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...
Jul 24, 20231 min read


Diabetic Foot Infection - #PHARMFAX
Diabetic foot infections are a significant contributer to osteomyelitis and lower extremity amputations. Diabetic foot infections are...
Jul 24, 20231 min read


Tranexamic Acid for Bradykinin-Induced Angioedema - #PHARMFAX
Tranexamic acid indirectly reduces bradykinin production by decreasing plasmin. Angioedema can be histamine or bradykin-mediated....
Jul 24, 20231 min read


Aortic Dissections - #PHARMFAX
Aortic dissections is a tear of the inner aortic wall that creates a “false lumen” and can potentially rupture. Aortic dissections is...
Jul 24, 20231 min read


Scorpion Antivenom- #PHARMFAX
Scorpion venom toxins inhibits inactivation of sodium channels, resulting in prolonged depolarization and autonomic excitation. Scorpion...
Jul 24, 20231 min read


Hydroxycobalamin and Vasoplegia - #PHARMFAX
High-dose hydroxycobalamin (vitamin B12) has an FDA indication for cyanide toxicity, but has seen increased use for refractory...
Jul 24, 20231 min read
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