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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Jul 27, 20231 min read
Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...


Jul 27, 20232 min read
Andexxa (Andexanet Alfa)
Andexxa (andexanet alfa) binds to anti-Xa inhibitors like apixaban and rivoraxaban to temporarily reverse their anticoagulant effects....


Jul 27, 20231 min read
ST-Elevation Myocardial Infarction - #PHARMFAX
ST-Elevation Myocardial Infarction (STEMI) primarily stems from complete occlusions of coronary arteries from plaque and clot deposits....


Jul 27, 20231 min read
IV Push Antihypertensives - #PHARMFAX
IV push antihypertensives are great tools to manage BP intermittently or bridge to titratable infusions. IV push antihypertensives are...


Jul 27, 20231 min read
Activated Charcoal - #PHARMFAX
Activated charcoal is most effective when given within 1 hour of toxic ingestions. Activated charcoal is most effective when given within...


Jul 26, 20231 min read
Acute Decompensated Heart Failure - #PHARMFAX
Severity of congestion and hypoperfusion determine guide our treatments in acute decompensated heart failure. Goals of therapy for...


Jul 25, 20231 min read
Class-Effect Anticholinergics - #PHARMFAX
Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for...


Jul 25, 20232 min read
Esmolol for Refractory VF/pVT - #PHARMFAX
After 3 defibrillations, 3 doses of epinephrine, and amiodarone or lidocaine administration puts us in the Refractory Ventricular...


Jul 25, 20231 min read
Calcium Salts and Massive Transfusion Protocol - #PHARMFAX
Reel and deal those calcium salts in massive transfusion protocol. Reel and deal those calcium salts in massive transfusion protocol....


Jul 25, 20231 min read
Normal Saline vs Lactated Ringers - #PHARMFAX
There has been a change of preference of fluids from normal saline to lactated ringers. There has been a change of preference of...


Jul 25, 20231 min read
Cannabinoid Hyperemsis Syndrome - #PHARMFAX
Maybe the devil’s lettuce is actually whats making you profusing vomit. Maybe the devil’s lettuce is actually whats making you profusing...


Jul 24, 20231 min read
Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...


Jul 24, 20232 min read
Urinary Tract Infections - #PHARMFAX
Bacteria in the urine without symptoms is not a urinary tract infection. Bacteria in the urine without symptoms is not a urinary tract...


Jul 24, 20232 min read
High-Dose Insulin for Overdoses - #PHARMFAX
BB and CCB overdoses progress into cardiogenic shock. BB inhibit catecholamines from binding to beta receptors, while CCB block SA and...


Jul 24, 20232 min read
Ketamine-Induced Laryngospasm - #PHARMFAX
Patients on ketamine can develop iatrogenic laryngospasm and hypersalivation. Patients on ketamine can develop iatrogenic laryngospasm...


Jul 24, 20231 min read
Bupropion Toxicity - #PHARMFAX
Wellbutrin was withdrawn from the market in 1986 due to high rates of seizures in a study on nondepressed bulimic patients. Wellbutrin...


Jul 24, 20231 min read
Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...


Jul 24, 20231 min read
Nonoccupational HIV Post-Exposure Prophylaxis - #PHARMFAX
28 days of antiretroviral prophylaxis is recommended for patients who seek medical treatment within 72 hours of high risk nonoccupational...


Jul 24, 20231 min read
Alcoholic Megaloblastic Anemia - #PHARMFAX
Alcoholism contributes to hematologic disorders, including anemia, leukopenia, and thrombocytopenia. Alcoholism contributes to...


Jul 24, 20231 min read
Diabetic Foot Infection - #PHARMFAX
Diabetic foot infections are a significant contributer to osteomyelitis and lower extremity amputations. Diabetic foot infections are...
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