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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.

Snake Envenomation - #PHARMFAX
Rattlesnakes, water moccasins, and copperheads are the more common species of concern in the United States. Rattlesnakes, water...
Jul 30, 20231 min read


Upcoming Weekly #PHARMFAX - 7.31.23
Take a sneak peak at the upcoming #PHARMFAX for the week, Make sure to participate in the #WYZESELECTION. Viewer choice, Instagram Poll...
Jul 29, 20231 min read

Physostigmine and Anticholinergic Toxidrome - #PHARMFAX
Physostigmine is a reversal agent for anticholinergic toxicities. Physostigmine is a reversal agent for anticholinergic toxicities. By...
Jul 28, 20231 min read


Open Fracture Prophylaxis - #PHARMFAX
Open fractures can lead to several complications, including compartment syndrome and osteomyelitis. Open fractures can lead to several...
Jul 27, 20231 min read


ESETT Secondary Antiepileptics - #PHARMFAX
The ESETT trial gave us a reminder that our secondary AEDs aren't very good. The ESETT trial gave us a reminder that our secondary AEDs...
Jul 27, 20231 min read


Phenobarbital for Severe Alcohol Withdrawal - #PHARMFAX
Phenobarbital is a great option to keep in your drug bank for severe alcohol withdrawal. Phenobarbital is a great option to keep in your...
Jul 27, 20231 min read


Acute Decompensated Heart Failure - #PHARMFAX
Severity of congestion and hypoperfusion determine guide our treatments in acute decompensated heart failure. Goals of therapy for...
Jul 26, 20231 min read


Class-Effect Anticholinergics - #PHARMFAX
Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for...
Jul 25, 20231 min read


Esmolol for Refractory VF/pVT - #PHARMFAX
After 3 defibrillations, 3 doses of epinephrine, and amiodarone or lidocaine administration puts us in the Refractory Ventricular...
Jul 25, 20232 min read


Ethanol Withdrawal Mechanism - #PHARMFAX
Two neurotransmitters that maintain neurochemical balance are GABA and glutamate, which are sedating and excitatory, respectively. Two ...
Jul 25, 20231 min read


Paxlovid (Nirmatrelvir and Ritonavir) - #PHARMFAX
Paxlovid reduces progression to severe COVID19 by 89% of mild cases. Paxlovid reduces progression to severe COVID19 by 89% of mild...
Jul 25, 20231 min read


Calcium Salts and Massive Transfusion Protocol - #PHARMFAX
Reel and deal those calcium salts in massive transfusion protocol. Reel and deal those calcium salts in massive transfusion protocol....
Jul 25, 20231 min read


Normal Saline vs Lactated Ringers - #PHARMFAX
There has been a change of preference of fluids from normal saline to lactated ringers. There has been a change of preference of...
Jul 25, 20231 min read


Cannabinoid Hyperemsis Syndrome - #PHARMFAX
Maybe the devil’s lettuce is actually whats making you profusing vomit. Maybe the devil’s lettuce is actually whats making you profusing...
Jul 25, 20231 min read


Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...
Jul 24, 20231 min read


High-Dose Insulin for Overdoses - #PHARMFAX
BB and CCB overdoses progress into cardiogenic shock. BB inhibit catecholamines from binding to beta receptors, while CCB block SA and...
Jul 24, 20232 min read


Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...
Jul 24, 20231 min read


Diabetic Foot Infection - #PHARMFAX
Diabetic foot infections are a significant contributer to osteomyelitis and lower extremity amputations. Diabetic foot infections are...
Jul 24, 20231 min read


Tranexamic Acid for Bradykinin-Induced Angioedema - #PHARMFAX
Tranexamic acid indirectly reduces bradykinin production by decreasing plasmin. Angioedema can be histamine or bradykin-mediated....
Jul 24, 20231 min read


Aortic Dissections - #PHARMFAX
Aortic dissections is a tear of the inner aortic wall that creates a “false lumen” and can potentially rupture. Aortic dissections is...
Jul 24, 20231 min read
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