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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Aug 3, 20231 min read
Bupropion Toxicity - #PHARMFAX
Wellbutrin was withdrawn from the market in 1986 due to high rates of seizures in a study on nondepressed bulimic patients. Wellbutrin...

Aug 3, 20231 min read
Oral Antihypertensive Pharmokinetics - #PHARMFAX
Acutely lowering blood pressure for hypertensive urgencies is commonly done without strong evidence. Acutely lowering blood pressure for...


Aug 3, 20231 min read
AmpC-Producing Beta-Lactamases - #PHARMFAX
AmpC-producing organisms make beta-lactam/beta-lactamase combos and most cephalosporins and penicillins ineffective. AmpC-producing...

Aug 1, 20231 min read
Serotonin Syndrome - #PHARMFAX
Serotonin syndrome presents with a triad of altered mental status, autonomic hyperactivity, and neuromuscular abnormalities. Serotonin...


Aug 1, 20231 min read
Unstable Tachyarrythmias - #PHARMFAX
Patients with an unstable tachyarrymthia need to be immediately cardioverted. Patients with an unstable tachyarrymthia need to be...

Jul 31, 20231 min read
Epididymo-Orchitis - #PHARMFAX
Target pathogens for epididmyitis and orchitis are dependent on patient risk factors. Target pathogens for epididmyitis and orchitis are...


Jul 31, 20231 min read
Nonoccupational HIV Post-Exposure Prophylaxis - #PHARMFAX
28 days of antiretroviral prophylaxis is recommended for patients who seen medical treatment within 72 hours of high risk...


Jul 31, 20231 min read
Canine Bites - #PHARMFAX
Children are more likely to experience dog bites and with greater severity compared to adults. Children are more likely to experience...

Jul 30, 20231 min read
Snake Envenomation - #PHARMFAX
Rattlesnakes, water moccasins, and copperheads are the more common species of concern in the United States. Rattlesnakes, water...


Jul 28, 20231 min read
Upcoming Weekly #PHARMFAX - 7.31.23
Take a sneak peak at the upcoming #PHARMFAX for the week, Make sure to participate in the #WYZESELECTION. Viewer choice, Instagram Poll...

Jul 28, 20231 min read
Physostigmine and Anticholinergic Toxidrome - #PHARMFAX
Physostigmine is a reversal agent for anticholinergic toxicities. Physostigmine is a reversal agent for anticholinergic toxicities. By...


Jul 27, 20231 min read
Open Fracture Prophylaxis - #PHARMFAX
Open fractures can lead to several complications, including compartment syndrome and osteomyelitis. Open fractures can lead to several...


Jul 27, 20231 min read
ESETT Secondary Antiepileptics - #PHARMFAX
The ESETT trial gave us a reminder that our secondary AEDs aren't very good. The ESETT trial gave us a reminder that our secondary AEDs...


Jul 26, 20231 min read
Acute Decompensated Heart Failure - #PHARMFAX
Severity of congestion and hypoperfusion determine guide our treatments in acute decompensated heart failure. Goals of therapy for...


Jul 25, 20231 min read
Class-Effect Anticholinergics - #PHARMFAX
Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for...


Jul 25, 20232 min read
Esmolol for Refractory VF/pVT - #PHARMFAX
After 3 defibrillations, 3 doses of epinephrine, and amiodarone or lidocaine administration puts us in the Refractory Ventricular...


Jul 25, 20231 min read
Ethanol Withdrawal Mechanism - #PHARMFAX
Two neurotransmitters that maintain neurochemical balance are GABA and glutamate, which are sedating and excitatory, respectively. Two ...


Jul 25, 20231 min read
Normal Saline vs Lactated Ringers - #PHARMFAX
There has been a change of preference of fluids from normal saline to lactated ringers. There has been a change of preference of...


Jul 24, 20231 min read
Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...


Jul 24, 20231 min read
Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...
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