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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Jul 25, 20232 min read
Esmolol for Refractory VF/pVT - #PHARMFAX
After 3 defibrillations, 3 doses of epinephrine, and amiodarone or lidocaine administration puts us in the Refractory Ventricular...


Jul 25, 20231 min read
Ethanol Withdrawal Mechanism - #PHARMFAX
Two neurotransmitters that maintain neurochemical balance are GABA and glutamate, which are sedating and excitatory, respectively. Two ...


Jul 25, 20231 min read
Protamine and Unfractionated Heparin - #PHARMFAX
Who would’ve known the drug that reverses unfractionated heparin derives from salmon sperm. Who would’ve known the drug that reverses...


Jul 25, 20231 min read
Calcium Salts and Massive Transfusion Protocol - #PHARMFAX
Reel and deal those calcium salts in massive transfusion protocol. Reel and deal those calcium salts in massive transfusion protocol....


Jul 25, 20231 min read
KCentra (4-Factor Prothrombin Complex Concentrate) - #PHARMFAX
KCentra (4-Factor Prothrombin Complex Concentrate) normalizes INR in roughly 30 minutes in the setting of life-threatening bleeds...


Jul 25, 20231 min read
Cannabinoid Hyperemsis Syndrome - #PHARMFAX
Maybe the devil’s lettuce is actually whats making you profusing vomit. Maybe the devil’s lettuce is actually whats making you profusing...


Jul 24, 20231 min read
Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...


Jul 24, 20231 min read
Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...


Jul 24, 20231 min read
Diabetic Foot Infection - #PHARMFAX
Diabetic foot infections are a significant contributer to osteomyelitis and lower extremity amputations. Diabetic foot infections are...


Jul 24, 20231 min read
Tranexamic Acid for Bradykinin-Induced Angioedema - #PHARMFAX
Tranexamic acid indirectly reduces bradykinin production by decreasing plasmin. Angioedema can be histamine or bradykin-mediated....


Jul 24, 20231 min read
Aortic Dissections - #PHARMFAX
Aortic dissections is a tear of the inner aortic wall that creates a “false lumen” and can potentially rupture. Aortic dissections is...


Jul 24, 20231 min read
Scorpion Antivenom- #PHARMFAX
Scorpion venom toxins inhibits inactivation of sodium channels, resulting in prolonged depolarization and autonomic excitation. Scorpion...


Jul 24, 20231 min read
Hydroxycobalamin and Vasoplegia - #PHARMFAX
High-dose hydroxycobalamin (vitamin B12) has an FDA indication for cyanide toxicity, but has seen increased use for refractory...
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