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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Bupropion Toxicity - #PHARMFAX
Wellbutrin was withdrawn from the market in 1986 due to high rates of seizures in a study on nondepressed bulimic patients. Wellbutrin...
Aug 3, 20231 min read

Oral Antihypertensive Pharmokinetics - #PHARMFAX
Acutely lowering blood pressure for hypertensive urgencies is commonly done without strong evidence. Acutely lowering blood pressure for...
Aug 3, 20231 min read


AmpC-Producing Beta-Lactamases - #PHARMFAX
AmpC-producing organisms make beta-lactam/beta-lactamase combos and most cephalosporins and penicillins ineffective. AmpC-producing...
Aug 3, 20231 min read


Severe Hypercalcemia - #PHARMFAX
Nearly 90% of patients with hypercalcemia have primary hyperparathyroidism or malignancy. Nearly 90% of patients with hypercalcemia have...
Aug 3, 20231 min read


Ethylene Glycol Toxicity - #PHARMFAX
Severe hypocalcemia, acute renal failure, seizures, and cardiopulmonary arrest occur at different stages with ethylene glycol toxicity....
Aug 3, 20231 min read

Serotonin Syndrome - #PHARMFAX
Serotonin syndrome presents with a triad of altered mental status, autonomic hyperactivity, and neuromuscular abnormalities. Serotonin...
Aug 2, 20231 min read


Ethylene Glycol Toxicity - #PHARMFAX
Severe hypocalcemia, acute renal failure, seizures, and cardiopulmonary arrest occur at different stages with ethylene glycol toxicity....
Aug 1, 20231 min read


Unstable Tachyarrythmias - #PHARMFAX
Patients with an unstable tachyarrymthia need to be immediately cardioverted. Patients with an unstable tachyarrymthia need to be...
Aug 1, 20231 min read


Clinical Use of IV Magnesium - #PHARMFAX
Magnesium is utilized acutely for asthma exacerbations, pre-eclampsia, arrythmias, migraines, and potassium absorption. Magnesium is...
Aug 1, 20231 min read

Epididymo-Orchitis - #PHARMFAX
Target pathogens for epididmyitis and orchitis are dependent on patient risk factors. Target pathogens for epididmyitis and orchitis are...
Aug 1, 20231 min read


Hypovolemic Shock - #PHARMFAX
Hypovolemic shock can categorized as non-hemorrhagic and hemorrhagic. Hypovolemic shock can categorized as non-hemorrhagic and...
Aug 1, 20231 min read


Nonoccupational HIV Post-Exposure Prophylaxis - #PHARMFAX
28 days of antiretroviral prophylaxis is recommended for patients who seen medical treatment within 72 hours of high risk...
Aug 1, 20231 min read


Chlamydia Trachomatis and Neisseria Gonorrheae - #PHARMFAX
Gonorrhea and chlamydia are the two most common STI in the US. Gonorrhea and chlamydia are the two most common STI in the US. Don’t...
Aug 1, 20231 min read


Canine Bites - #PHARMFAX
Children are more likely to experience dog bites and with greater severity compared to adults. Children are more likely to experience...
Aug 1, 20231 min read

Physostigmine and Anticholinergic Toxidrome - #PHARMFAX
Physostigmine is a reversal agent for anticholinergic toxicities. Physostigmine is a reversal agent for anticholinergic toxicities. By...
Jul 28, 20231 min read


Open Fracture Prophylaxis - #PHARMFAX
Open fractures can lead to several complications, including compartment syndrome and osteomyelitis. Open fractures can lead to several...
Jul 27, 20231 min read


ESETT Secondary Antiepileptics - #PHARMFAX
The ESETT trial gave us a reminder that our secondary AEDs aren't very good. The ESETT trial gave us a reminder that our secondary AEDs...
Jul 27, 20231 min read


Phenobarbital for Severe Alcohol Withdrawal - #PHARMFAX
Phenobarbital is a great option to keep in your drug bank for severe alcohol withdrawal. Phenobarbital is a great option to keep in your...
Jul 27, 20231 min read


Acute Decompensated Heart Failure - #PHARMFAX
Severity of congestion and hypoperfusion determine guide our treatments in acute decompensated heart failure. Goals of therapy for...
Jul 26, 20231 min read


Esmolol for Refractory VF/pVT - #PHARMFAX
After 3 defibrillations, 3 doses of epinephrine, and amiodarone or lidocaine administration puts us in the Refractory Ventricular...
Jul 25, 20232 min read
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