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PHARMWYZE
Concise. Informative. Efficient.
The weekly newsletter recapping prior week's PHARMWYZE SO. content.


Jul 25, 20231 min read
KCentra (4-Factor Prothrombin Complex Concentrate) - #PHARMFAX
KCentra (4-Factor Prothrombin Complex Concentrate) normalizes INR in roughly 30 minutes in the setting of life-threatening bleeds...


Jul 25, 20231 min read
Cannabinoid Hyperemsis Syndrome - #PHARMFAX
Maybe the devil’s lettuce is actually whats making you profusing vomit. Maybe the devil’s lettuce is actually whats making you profusing...


Jul 24, 20231 min read
Viral Encephalitis - #PHARMFAX
Acyclovir reduced mortality from herpes simplex encephalitis from 70% to 9%. Thats pretty good. The introduction of acyclovir reduced...


Jul 24, 20232 min read
Urinary Tract Infections - #PHARMFAX
Bacteria in the urine without symptoms is not a urinary tract infection. Bacteria in the urine without symptoms is not a urinary tract...


Jul 24, 20232 min read
High-Dose Insulin for Overdoses - #PHARMFAX
BB and CCB overdoses progress into cardiogenic shock. BB inhibit catecholamines from binding to beta receptors, while CCB block SA and...


Jul 24, 20232 min read
Ketamine-Induced Laryngospasm - #PHARMFAX
Patients on ketamine can develop iatrogenic laryngospasm and hypersalivation. Patients on ketamine can develop iatrogenic laryngospasm...


Jul 24, 20231 min read
Bupropion Toxicity - #PHARMFAX
Wellbutrin was withdrawn from the market in 1986 due to high rates of seizures in a study on nondepressed bulimic patients. Wellbutrin...


Jul 24, 20231 min read
Extended-Spectrum Beta-Lactamase - #PHARMFAX
Extended-spectrum beta-lactamase organisms hydrolyze penicillins, cephalosporins, and aztreonam. Extended-spectrum beta-lactamase...


Jul 24, 20231 min read
Nonoccupational HIV Post-Exposure Prophylaxis - #PHARMFAX
28 days of antiretroviral prophylaxis is recommended for patients who seek medical treatment within 72 hours of high risk nonoccupational...


Jul 24, 20231 min read
Alcoholic Megaloblastic Anemia - #PHARMFAX
Alcoholism contributes to hematologic disorders, including anemia, leukopenia, and thrombocytopenia. Alcoholism contributes to...


Jul 24, 20231 min read
Diabetic Foot Infection - #PHARMFAX
Diabetic foot infections are a significant contributer to osteomyelitis and lower extremity amputations. Diabetic foot infections are...


Jul 24, 20231 min read
Tranexamic Acid for Bradykinin-Induced Angioedema - #PHARMFAX
Tranexamic acid indirectly reduces bradykinin production by decreasing plasmin. Angioedema can be histamine or bradykin-mediated....


Jul 24, 20231 min read
Aortic Dissections - #PHARMFAX
Aortic dissections is a tear of the inner aortic wall that creates a “false lumen” and can potentially rupture. Aortic dissections is...


Jul 24, 20231 min read
Scorpion Antivenom- #PHARMFAX
Scorpion venom toxins inhibits inactivation of sodium channels, resulting in prolonged depolarization and autonomic excitation. Scorpion...


Jul 24, 20231 min read
Hydroxycobalamin and Vasoplegia - #PHARMFAX
High-dose hydroxycobalamin (vitamin B12) has an FDA indication for cyanide toxicity, but has seen increased use for refractory...

Feb 27, 20237 min read
Cleviprex (clevidipine) Review | #MEDSHED
My favorite lipid emulsion for hypertensive emergencies — keep the propofol for sedation I have no relationships to report with the drug...
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