Rapid Infusion IV Magnesium Sulfate Indications - #MEDSHED

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Magnesium is utilized acutely for asthma exacerbations, pre-eclampsia, arrythmias, migraines, and potassium absorption. The mechanism is likely multifactorial from physiologic calcium antagonism, endothelium-derived nitric oxide, and role as an important metabolic cofactor. Intracellular magnesium binds to ATP, making it biologically active. Magnesium is utilized acutely for asthma exacerbations, pre-eclampsia, arrythmias, migraines, and potassium absorption.

Rapid IV magnesium has shown to decrease the need for hospitalization in asthma exacerbations, superior for seizure prevention in pre-eclampsia, effectively treat atrial fibrillaton and TdP, and reduce migraine attacks/severity. Magnesium is also important in hypokalemia as it serves as a cotransporter for potassium absorption.

Safety always first; rapid infusions may cause hypotension, and never magnesium undiluted out of a vial.

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