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Writer's pictureMark Nguyen, PharmD, BCEMP

KCentra (4-Factor Prothrombin Complex Concentrate) - #PHARMFAX

KCentra (4-Factor Prothrombin Complex Concentrate) normalizes INR in roughly 30 minutes in the setting of life-threatening bleeds and/or emergent procedures.

 


KCentra (4-Factor Prothrombin Complex Concentrate) normalizes INR in roughly 30 minutes in the setting of life-threatening bleeds and/or emergent procedures. KCentra can also be used off-label to overcome coagulopathies secondary to DOACs, specifically apixaban and rivaroxaban, with clotting factors. KCentra contains clotting factor 2, 7, 9, 10, protein c and s, and heparin The benefits of KCentra often outweigh the risk of venous thomboembolism, but make sure to follow up on monitoring. KCentra is also contraindicated in those with a history of HITT. For more PHARMFAX in the drug bank, go ahead and visit my website, link in my bio. All PHARMWYZE SOURCE www.pharmwyze.com References can also be found on website #doacs #kcentra #4fpcc #pharmacy #twitterx #emergencymedicine #criticalcare #reversalagents Not medical advice. Educational purposes only. No relationships to report. I hope you learned something new.

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