Welcome to the #MEDIGRAM Patient Case: Chief Compliant Series. Short, concise patient cases to foster thought-provoking questions and to challenge you to ask questions! Make sure to by at the end of the week for explanations for the correct/incorrect answers.
đ± Patient Case CC: Radiating Chest Pain [Explanation] - #MEDIGRAM
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đ Which P2Y12 inhibitor should be avoided?
Clopidogrel: slow onset of action (~ 2 hours) compared to the less than 30 mins of ticagrelor and prasugrel. It is also extensively metabolized by CYP2C19.
Ticagrelor: BID frequency compared to the daily of the clopidogrel and prasugrel.
Prasugrel: Biggest concern is the contraindication in patients with a hx of stroke or TIA due to the increased risk of bleeding. Caution should also be used in elderly patients.
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