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Writer's pictureMark Nguyen, PharmD, BCEMP

Class-Effect Anticholinergics - #PHARMFAX

Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for additive effects.

 

Just because something is available over the counter, doesn’t necesarily mean it’s safe for complex patients and/or account for additive effects. The example we’ll use include anticholinergics and their toxidrome. This results from acetylcholine accumulation since anticholinergics block the activity of acetylcholine. Anticholinergics cause dry mouth, blurry vision, confusion, delirium, difficulty urinating, constipation, and fast heart rate. The class effect of anticholinergics can be remembered with this mneuomonic: red as a beet, dry as a bone, blind as a bat, mad as a hatter, hot as a hare, full as a flask. Benadryl, Zyrtec, Loratadin, Allegra, and Unison are common OTC anticholinergics used for allergies and sleep aids. Its important to note that many prescribed antidepressants, muscle relaxers, and antipsychotics have anticholinergic properties as a secondary mechanism. Severe cases may lead to seizures. We have an antidote called physostigmine that is indicated more for minimizing copious amounts of sedatives for acute agitation and delirium, and doesn’t have any anticonvulsant properties. For more PHARMFAX in the drug bank, tag a friend who is a healthcare professional or student, so we can deposit in their drug bank. ALL PHARMWYZE SOURCE www.pharmwyze.com References can be found on website. Follow me @pharmwyze Twitter | Facebook | TikTok | YouTube | Instagram #medicine #medicalschool #pharmacy #pharmacyschool #studentpharmacist #nursing #nursingschool #medicalstudent #pa #physicianassistant #pharmwyze #pharmfax #pharmfaxinthedrugbank Not medical advice. Educational purposes only. No relationships to report. I hope you learned something new today. Think I deserve a tip? Website: https://www.pharmwyze.com/donate Crypto (BTC/ETH/USDC): 0x9edC9b21dC18Da768c714f7f7a844217246bA7a5 Paypal: https://www.paypal.com/donate/?hosted_button_id=XUBQCDKNF4B8U

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